WebWe report here polymersomes that can protect biomolecules in the extracellular environment, are taken up by endocytosis, and then suddenly burst within the early endosome, releasing their contents prior to exposure to the harsh conditions encountered after lysosomal fusion. WebDec 19, 2024 · Accordingly, we will discuss four types of protocells in the following sections: protocells programmed by genetic circuitry, protocells programmed by enzyme-assisted non-genetic circuitry, protocells propelled by prebiotically mimicked reaction networks and protocells equipped with DNA dynamic circuitry ( Fig. 1 ).

Protocells programmed through artificial reaction networks

WebJul 7, 2011 · Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be … WebSemantic Scholar extracted view of "Towards an artificial cell" by D. Hammer et al. cedar creek lake wma

Engineering Polymersome Protocells - ResearchGate

WebDec 3, 2009 · Here, the facile synthesis of a composite MR contrast platform is described; it consists of dendrimer conjugates encapsulated in porous polymersomes. These nanoparticles exhibit improved permeability to water flux and a large capacity to store chelated Gd within the aqueous lumen, resulting in enhanced longitudinal relaxivity. WebMar 20, 2024 · For this purpose, an overaching concept for engineering synthetic compartments from polymeric materials and biomaterials has been stablished for numerous practical applications, such as in biosynthesis, gene therapy, tissue engineering, or … butter on burns