Rbm10 and hcc
WebJun 1, 2024 · Download Citation Protective effect of the RNA-binding protein RBM10 in hepatocellular carcinoma Objective: To illustrate the protective effect of RBM10 on … WebMay 22, 2013 · Hepatocellular carcinoma (HCC) is one of the most common and aggressive cancers and is associated with a poor survival rate. Clinically, the level of alpha-fetoprotein (AFP) has been used as a biomarker for the diagnosis of HCC. The discovery of useful biomarkers for HCC, focused solely on the proteome, has been difficult; thus, wide-ranging …
Rbm10 and hcc
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WebOverexpression of RBM5 or RBM10 both consistently resulted in relatively high levels of Fas −exon 6 transcripts which encoded soluble and antiapoptotic isoforms in different cells . … Websplicing, human RBM10 was also found to be part of histone H2A deubiquitinase complex (36), suggesting a role in linking splicing and chromatin regulation. In this study, we …
WebOverexpression of RBM10 can reduce the protein levels of EGFR and p-ERK, inhibit the proliferation of HCCs, and induce apoptosis, while also inhibiting cell invasion . As a tumor … WebJul 7, 2024 · Identification of potential genetic modifiers of EGFR inhibitor response highlights RBM10. Oncogenic EGFR-activating mutations are associated with high initial …
WebJan 19, 2024 · Deletion of rbm10 + induces minor changes in gene expression and intron retention. To further understand the role of Rbm10, we constructed a deletion strain, … WebFeb 24, 2024 · The RNA-binding motif protein 10 (RBM10) is involved in alternative splicing and modifies mRNA post-transcriptionally. RBM10 is abnormally expressed in the lung, …
WebThe prognostic potential of RBM10 in HCC was assessed via the Kaplan-Meier method. Overexpression of RBM10 was achieved by transfection of LV-RBM10 in HepG2 and HCC …
WebOverexpression of RBM10 can reduce the protein levels of EGFR and p-ERK, inhibit the proliferation of HCCs, and induce apoptosis, while also inhibiting cell invasion . As a tumor suppressor gene, RBM10 can reduce the malignant progression of HCC and is a novel prognostic biomarker and therapeutic target in patients with liver cancer. ipad could not be restored 3194WebMeanwhile, overexpressing RBM10 could promote the proliferation, migration and invasion of Hep G2 cells; while the stability of miR-21 could be reduced by knocking down RBM10. … ipad countdown widgetWebJun 4, 2024 · The French AFP model 3 and the Metroticket 2.0 model 1 both demonstrate that a combination of AFP and tumor burden parameters predicts post-LT outcome far better than tumor burden alone. For example, using the Metroticket 2.0 calculator, a patient with a single 7-cm tumor and AFP of 5 ng/mL would have an excellent 85% predicted 5 … ipad cost in ukWebMar 1, 2024 · Overexpression of RBM10 was achieved by transfection of LV-RBM10 in HepG2 and HCC-LM3 cells. Cell counting kit-8 (CCK-8) assay and flow cytometry were … ipad could not be restored error 3194WebIntegrated Bioinformatics Analysis and Validation of the Prognostic Value of RBM10 Expression in Hepatocellular Carcinoma Pang SJ, Sun Z, Lu WF, Si-Ma H, Lin ZP, Shi Y, … ipad counter stand swivelWebApr 10, 2024 · RNR1 and hexokinase 2 (HK2) are important risk factors in hepatocellular carcinoma (HCC) patients . RNR2 plays an anti-apoptotic role by avoiding deploying … open marylandWebIn contrast, overexpressed RBM10 restrained virus replication by preventing SAT1 from splicing, which uncovered the antiviral effect of RBM10 targeting SAT1. Other Viruses. … open martin luther king day